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Project TitleGTPase Fluorescent Dye Conjugates as Indicators of Nucleotide State
Track Code2000-020
Short DescriptionThe nucleotide state of small GTPase signaling molecules can be reported by a fluorescent analog of the small GTPase protein. The fluorescent readout from this analog can be used for in vivo screens
AbstractThe nucleotide state of small GTPase signaling molecules can be reported by a fluorescent analog of the small GTPase protein. The fluorescent readout from this analog can be used for in vivo screens where this biological behavior is a valuable readout. The fluorescent dye is attached to the GTPase in a position where it responds to protein structural changes induced by GTP binding.
 
TagsNone
 
Posted DateFeb 9, 2012 9:08 PM

Researcher

Name
Larry Gerace
Klaus Hahn

Manager

Name
Sharon Kwan